abstract：:The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fisc...

journal_title：Natural product research

authors： Bruno M,Fiori M,Mattei D,Melchiorre S,Messineo V,Volpi F,Bogialli S,Nazzari M

更新日期：2006-07-20 00:00:00

abstract：:The phytochemical study of the aerial parts of Viburnum chinshanense Graebn., a species growing in Western and Central China, led to the isolation of six iridoid glucosides: the novel 10,2'-diacetylpatrinoside, 1, and the known 2'-acetyldihydropenstemide, 2'-trans- p-coumaroyl-dihydropenstemide, 2'-acetylpatrinoside, ...

journal_title：Natural product research

authors： Tomassini L,Gao J,Foddai S,Serafini M,Ventrone A,Nicoletti M

更新日期：2006-07-10 00:00:00

abstract：:Microwave assisted Diels-Alder cycloaddition of 5-Br-N-benzylpyridinone (2) with methyl acrylate is described to gain an easy access to 7-bromo-2-benzyl-3-oxo-2-aza-5 or 6-carbomethoxy bicyclo[2.2.2]oct-7-enes (3)-(6). The preparation of the ibogaine analogue 20-desethyl-(20-endo)-hydroxymethyl-11-demethoxyibogaine (1...

journal_title：Natural product research

authors： Passarella D,Barilli A,Efange SM,Elisabetsky E,Leal MB,Lesma G,Linck VM,Mash DC,Martinelli M,Peretto I,Silvani A,Danieli B

更新日期：2006-07-10 00:00:00

abstract：:Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was s...

journal_title：Natural product research

authors： Miyazawa M,Kohno G,Okuno Y,Oda Y

更新日期：2006-06-01 00:00:00

abstract：:A novel butenoate derivative, methyl (Z)-4-{[(Z)-1-(hydroxymethyl)-2-phenyl-1-ethenyl] amino}-4-oxo-2-butenoate (1), was isolated from the fermentation broth of an Aspergillus niger strain Ta1. The structure (1) was elucidated by spectral analysis. Bioassays showed that compound 1 had a weak antioxidant activity. ...

journal_title：Natural product research

authors： Yuan W,Zhu H,Cheng K,Huang Z,Qin Y,Yang J,Zhu P

更新日期：2006-05-20 00:00:00

abstract：:The iridoidic composition of Stachys glutinosa L. was examined in comparison with the results obtained in the phytochemical studies on S. corsica Pers. The presence of the known harpagide and acetyl-harpagide were showed together with that of a new di-glycosidic iridoid. The structure of this new compound, the 5-allos...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M,Bianco A

更新日期：2006-05-20 00:00:00

abstract：:Cyanamide (NH(2)CN) has recently been isolated as a plant growth inhibitor from Vicia villosa, which is the first discovery of cyanamide from natural sources. To reveal the presence of the biosynthesized cyanamide in plants, 3.4 mM potassium ((15)N)nitrate was administered to 15- to 35-day-old plants of V. villosa, fr...

journal_title：Natural product research

authors： Kamo T,Kato K,Hiradate S,Nakajima E,Fujii Y,Hirota M

更新日期：2006-05-10 00:00:00

abstract：:4-Methoxybenzene-1-ONN-azoxyformamide (1), 4-methoxybenzene-1-azoformamide (2), 4-hydroxyben-zene-1-azoformamide (3) and 4-hydroxybenzene-1-ONN-azoxyformamide (4) were isolated from the fruiting bodies of Calvatia craniiformis and Lycoperdon hiemale, respectively. Compounds 1 and 4 showed radicle growth inhibitory act...

journal_title：Natural product research

authors： Kamo T,Kashiwabara M,Tanaka K,Ando S,Shibata H,Hirota M

更新日期：2006-05-10 00:00:00

abstract：:Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...

journal_title：Natural product research

authors： Komala I,Rahmani M,Sukari MA,Mohd Ismail HB,Cheng Lian GE,Rahmat A

更新日期：2006-04-01 00:00:00

abstract：:Phebaclavin I, a novel 3-prenylated coumarin, was isolated from the aerial parts of Phebalium aff. tuberculosum (Rutaceae) together with five known related compounds, Phebaclavin A, B, D, G, H. The structure of phebaclavin I was established by spectroscopic methods. Several other known coumarins were obtained, includi...

journal_title：Natural product research

authors： Roux D,Muyard F,Girard C,Colombain M,Tillequin F,Waterman PG,Bévalot F

更新日期：2006-03-01 00:00:00

abstract：:To search for possible cancer chemopreventive agents from natural sources, we performed primary screening of metabolites of Alternaria porri by examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. The et...

journal_title：Natural product research

authors： Horiuchi M,Tokuda H,Ohnishi K,Yamashita M,Nishino H,Maoka T

更新日期：2006-02-01 00:00:00

abstract：:From the aerial parts of Citharexylum spinosum L., one new iridoid glucoside, the 7-ss-O-acetate (1) of lamiide, along with four known iridoid glucosides, lamiide (2), lamiidoside (3), duranterectoside C (4), 8-epiloganin (5) and one known lignan glucoside (+)-lyonirenisol-3a-O-ss-D-glucopyranoside (6) were isolated. ...

journal_title：Natural product research

authors： Balázs B,Tóth G,Duddeck H,Soliman HS

更新日期：2006-02-01 00:00:00

abstract：:Extracts obtained from Cyrtocarpa procera Kunth were evaluated to determine their toxicity on Artemia salina Leach. All the extracts showed a significant activity. Bioguided fractionation of these extracts led to the isolation of beta-sitosterol and the identification of 1,3-propyl-dipentadecanoate, 3-hydroxypropyl-9-...

journal_title：Natural product research

authors： Rodríguez-López V,Aguirre-Crespo F,Salazar L,Estrada-Soto S

更新日期：2006-01-01 00:00:00

abstract：:Two new flavonoids, 8-hydroxyisoscoparin (1) and luteolin 7-O-glucoside 4''-sulfate (2), along with eight known flavonoids, including luteolin 7-O-glucoside 2''-sulfate, were isolated and identified from Washingtonia filifera. All compounds were characterized by (1)H-NMR, (13)C-NMR, CI-MS, FABMS and UV. The antioxidan...

journal_title：Natural product research

authors： El-Sayed NH,Ammar NM,Al-Okbi SY,El-Kassem LT,Mabry TJ

更新日期：2006-01-01 00:00:00

abstract：:The hexane fraction from the roots of Echinops ellenbeckii O. Hoffm. from Ethiopia yielded seven acetylenic thiophenes of which five compounds (1, 3, 4, 6, 7) are reported for the first time in this species: the monothiophenes 5-(penta-1,3-diynyl)-2-(but-3-en-1-ynyl)-thiophene (1), 5-(penta-1,3-diynyl)-2-(4-acetoxy-bu...

journal_title：Natural product research

authors： Hymete A,Rohloff J,Kjøsen H,Iversen TH

更新日期：2005-12-01 00:00:00

abstract：:A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

journal_title：Natural product research

authors： Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

更新日期：2005-10-01 00:00:00

abstract：:Two flavonoid glycosides containing acetylated allose, and two iridoid glucosides were obtained from a EtOH extract of Stachys corsica, an endemic plant of Sardinia and Corsica. All the compounds have previously been isolated from other species of Stachys. ...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M

更新日期：2005-09-01 00:00:00

abstract：:The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments. ...

journal_title：Natural product research

authors： Siddiqui BS,Arfeen S,Begum S,Sattar FA

更新日期：2005-09-01 00:00:00

abstract：:Specimens of the cosmopolitan sea hare Aplysia parvula, collected in the Tsistsikamma National Park on the south-east coast of South Africa yielded the new dibromo-C15-acetogenin, (3Z)-bromofucin (1). Standard spectroscopic methods were used to establish the structure of this compound. ...

journal_title：Natural product research

authors： McPhail KL,Davies-Coleman MT

更新日期：2005-07-01 00:00:00

abstract：:Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

journal_title：Natural product research

authors： Deota PT,Upadhyay PR

更新日期：2005-07-01 00:00:00

abstract：:The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...

journal_title：Natural product research

authors： Patro BS,Chintalwar GJ,Chattopadhyay S

更新日期：2005-06-01 00:00:00

abstract：:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...

journal_title：Natural product research

authors： Balas L,Hellal M,Rossi JC,Durand T

更新日期：2005-06-01 00:00:00

abstract：:Two new myrsinol-type diterpene polyesters 3,5,13,17-tetra-O-acetyl-7-O-benzoyl-15-hydroxymyrsinol (1) and 3,5,13,17-tetra-O-acetyl-7-O-butanoyl-13-hydroxymyrsinol (2), with a tricyclic carbon skeleton have been isolated from Euphorbia decipiens Boiss. & Buhse. The structure elucidation of the isolated compounds was b...

journal_title：Natural product research

authors： Ahmad VU,Hussain J,Hussain H,Farooq U,Farmanullah,Lodhi MA,Choudhary MI

更新日期：2005-04-01 00:00:00

abstract：:In this study, phenolic compounds of hazelnut leaves of 10 different cultivars with the same cultural, geographical, geological and climatic conditions were analyzed by HPLC/DAD and HPLC/DAD/MS/MS - ESI. Eight phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, caffeoyltartaric acid, p-coumaroyltartaric ...

journal_title：Natural product research

authors： Amaral JS,Ferreres F,Andrade PB,Valentão P,Pinheiro C,Santos A,Seabra R

更新日期：2005-02-01 00:00:00

abstract：:The ethanolic extract of the bulbs of Fritillaria imperialis was subjected to fractionation by solvent-solvent extraction. The nonpolar fraction showed inhibitory activity against prolyl endopeptidase (PEP) (EC.3.4.21.26), a large intracellular enzyme that preferentially hydrolyze proline-containing oligopeptidase at ...

journal_title：Natural product research

authors： Atta-ur-Rahman,Akhtar MN,Choudhary MI,Tsuda Y,Yasin A,Sener B,Parvez M

更新日期：2005-01-01 00:00:00

abstract：:The isolation from olive pulp of a diacylglycerol showing an oleic as well as an elenoic acid residue, the latter probably derived from a natural enzymatic oleuropein hydrolysis, is reported. The given structure is supported by 1H- and 13C-NMR data. ...

journal_title：Natural product research

authors： Marra C,Giordano ME

更新日期：2005-01-01 00:00:00

abstract：:Fermentation of (+)-androst-4-ene-3,17-dione (1) with Curvularia lunata for 10 days yielded five oxidative and reductive metabolites, androsta-1,4-diene-3,17-dione (2), 17beta-hydroxyandrosta-1,4-dien-3-one (3), 11alpha-hydroxyandrost-4-ene-3,17-dione (4), 11alpha,17beta-dihydroxyandrost-4-en-3-one (5) and 15alpha-hyd...

journal_title：Natural product research

authors： Choudhary MI,Sultan S,Khan MT,Yasin A,Shaheen F,Atta-ur-Rahman

更新日期：2004-12-01 00:00:00

abstract：:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...

journal_title：Natural product research

authors： Benkendorff K,Pillai R,Bremner JB

更新日期：2004-10-01 00:00:00

abstract：:A new 1,4-phenanthraquinone was isolated from the roots of Menispermum dauricum. The structure was elucidated as 7-hydroxy-3,6-dimethoxy-1,4-phenanthraquinone on the basis of spectral evidence. ...

journal_title：Natural product research

authors： Zhang ZJ,Zhang XQ,Ye WC,Wang Y,Che CT,Zhao SX

更新日期：2004-08-01 00:00:00

abstract：:In order to identify genes related to Taxol biosynthesis, the mRNA differential display method was employed to compare mRNA populations from suspension cultured Taxus chinensis cells before and after beginning to produce Taxol. From a total display of about 4000 PCR products, 104 were derived from cells during the Tax...

journal_title：Natural product research

authors： Hu G,Fan T,Mei X

更新日期：2004-08-01 00:00:00

abstract：:An aroma chemical emitted from Gerris paludum insularis was analyzed by means of GC and GC-MS. The main constituent was identified as iso amyl alcohol (3-methyl-1-butanol). The chemical showed a characteristic aroma of Gerris paludum insularis. ...

journal_title：Natural product research

authors： Ono T,Miyazawa M

更新日期：2004-06-01 00:00:00

abstract：:Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp. In addition, another new benzoic acid 10 with an unusual 1,2-dicarbonyl side chain was indirectly identified from its...

journal_title：Natural product research

authors： Krohn K,Sohrab MH,Aust HJ,Draeger S,Schulz B

更新日期：2004-06-01 00:00:00

abstract：:Two new norsesquiterpenes were isolated from the extracts of the roots and rhizomes of Ligularia lapathifolia (Franch.) Hand.-Mazz. Their structures were identified as 2-acetyl-3a-methyl-5-(2-methyl-but-2-enoyloxy)-3a,4,5,6,7,7a-hexahydro-H-indene-4-carboxylic acid (1) and 2-acetyl-8a-methyl-2-(2-methyl-but-2-enoyloxy...

journal_title：Natural product research

authors： Li YS,Wang ZT,Zhang M,Chen JJ,Luo SD

更新日期：2004-04-01 00:00:00

abstract：:A new alkaloid, namely laccarin A (1), along with four known alkaloids, laccarin (2), adenosine (3), indole-3-carboxaldehyde (4) and nicotinamide (5), was isolated from the fungus Lactarius subplinthogalus. The structure of laccarin A (1) was established mainly by spectroscopic methods. ...

journal_title：Natural product research

authors： Wang Y,Yang SP,Wu Y,Yue JM

更新日期：2004-04-01 00:00:00

abstract：:The CDC25 phosphatases regulate the cell division cycle by controlling the activity of cyclin-dependent kinases. While screening for inhibitors of phosphatases among natural products we repeatedly found that some polyprenyl-hydroquinones and polyprenyl-furans (furanoterpenoids) (furospongins, furospinosulins) were pot...

journal_title：Natural product research

authors： Erdogan-Orhan I,Sener B,de Rosa S,Perez-Baz J,Lozach O,Leost M,Rakhilin S,Meijer L

更新日期：2004-02-01 00:00:00

abstract：:A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of th...

journal_title：Natural product research

authors： Rahmani M,Leng KW,Ismail HB,Hin TY,Sukari MA,Ali AM,Kulip J

更新日期：2004-02-01 00:00:00

abstract：:Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...

journal_title：Natural product research

authors： Hsieh PW,Chang FR,McPhail AT,Lee KH,Wu YC

更新日期：2003-12-01 00:00:00

abstract：:From the leaves of Mallotus apelta two new benzopyran compounds (1,2) were obtained and their structures were determined using spectroscopic methods. ...

journal_title：Natural product research

authors： An TY,Hu LH,Cheng XF,Chen ZL

更新日期：2003-10-01 00:00:00

abstract：:A phytochemical reinvestigation of the whole plant of Euphorbia segetalis yielded five tetracyclic triterpenes: 3beta-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3beta,24-diol (2), cycloart-23-ene-3beta,25-diol (3), lanosta-7,9(11),24-trien-3beta-ol (4) and lanosta-7,9(11),24(31)-trien-3beta-ol (5). beta-acetox...

journal_title：Natural product research

authors： Madureira AM,Ascenso JR,Valdeira L,Duarte A,Frade JP,Freitas G,Ferreira MJ

更新日期：2003-10-01 00:00:00

abstract：:Two new steroidal alkaloids, salonine-A [(20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta,4beta-diol] (1), and salonine-B [(20S)-20-(N,N-dimethylamino)-3beta-methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Thei...

journal_title：Natural product research

authors： Atta-ur-Rahman,Feroz F,Zaheer-ul-Haq,Nawaz SA,Khan MR,Choudhary MI

更新日期：2003-08-01 00:00:00